Study objective:
@EN To comparative study the results between hyperbaric oxygen therapy and non-hyperbaric oxygen therapy in the these patients, because controversy exists regarding hyperbaric therapy in the drowsy patient with carbon monoxide intoxication
@ES Design:
@EN Retrospective study
@ES Setting:
@EN The WonKwang university hospital emergency department during january first 1991 through June 31th 1995.
@ES Method and result:
@EN According to history and carboxyhemoglobin level, we experienced 105 patients of carbon monoxide intoxication admitted to emergency department. Patients intoxicated by other gases and death patients before admission was excluded. According to
the
indication of the hyperbaric oxygen therapy on carbon monoxide intoxication, 15 patients among 16 patients with coma, semicoma, and stuporous mental state was done. Patient with drowsy mental state was 23 patients, 6 of these patients was done
hyperbaric oxygen therapy and remainder was not. Charts of patients with carbon monoxide intoxication including patients with drowsy mental state was reviewed to determine the result between hyperbaric oxygen therapy and non-hyperbaric oxygen
therapy.
According to clinical leatures, we found sex ratio(1:1.6), mean age(35.1±19.4years), age range from 1 to 85 years old, 41cases(39%) in 1991, 66cases(62.9%) in alert mental state and 23cases(21.9%) in drowsy mental state The exposure time and
time
until
alert mental status by mental status were 9.5±0.67hours, 18.8±28.3hours in coma mental status. The early laboratory findings were leukocytosis in 39cases(37.1%), increased hematocrit in 20cases(19.1%), increased GOT in 14cases(13.85), increased
GPT in
12cases(11.4%), increased creatinine in 10 cases(9.5%), glucosuria in 17cases(16.2%) and normal arterial blood gas analysis findings except acidemia in drowsy and coma mental status, and most common abnormal findings were seen in stuporous mental
status. The exposure time and time and time until alert mental status by carboxyhemoglobin concentration were no significant statistical results, and time until alert mental status between drowsy and stuporous mental status with hyperbaric oxygen
therapy were 3.9±3.04hours. In patients with drowsy mental status, the patients with hyperbaric oxygen therapy that was 3.9±3.04hours in time until alert mental status, 1cases(17%) in carboxyhemoglobin concentration(≥20%), 5cases(83%) in
carboxyhemoglobin concentration(<20%), 1.43≥2.11days in admission period, and patients without hyperbaric oxygen therapy were 9.9±6.04hours in the time until alert mental status. Arterial blood gas analysis between patients with and without
hyperbaric
oxygen therapy in drowsy mental status were normal findings except acidemia before hyperbaric oxygen therapy. The comparison between hyperbaric oxygen therapy and non hyperbaric oxygen therapy in patients with drowsy mental status were
significant
statistical result in time until alert mental status.
@ES Conclusion:
@EN Although hyperbaric oxygen therapy was done according to the indication in carbon monoxide poisoning, these result imply that hyperbaric oxygen therapy is more important than the pure oxygen therapy in patients with drowsy mental status.
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